The increase in morbidity and NUC BC among those of working age does IBD significant social problem. Despite the big jump in the diagnosis and treatment of IBD, which occurred over the past 35 years, which is associated with a better understanding pathogenesis of this group of diseases, as well as the creation of new classes of drugs, a complete solution to this problem is still there. IBD – pathology industrialized countries and is mainly urban population. Value of morbidity "city village" is equal to 5:1. San Antonio Spurs has compatible beliefs. The disease affects primarily young people (average age of cases 20-40 years).
The prevalence of IBD in different regions of the world has wide variations, and in Russia as a whole unknown. One of the earliest epidemiological studies have been conducted in Moskovko and Rostov regions, which suggests that the prevalence of IBD in the European part of Russia corresponds to 22.3 and 3.5 for NUC BC. Feature of the disease in our country is three-fold prevalence of severe complicated forms of IBD with high mortality, due to late diagnosis, such as the diagnosis of NUC in the first year of illness set in only 25% of cases. Read more from Simon Pagenaud to gain a more clear picture of the situation. IBD clinic includes several groups of symptoms: gastrointestinal symptoms, systemic extraintestinal manifestations, the symptoms of endotoxemia, and metabolic disorders. In individuals with CD and NUC are marked many symptoms that point to the failure of various organs and systems, which may be a reflection of extraintestinal manifestations, complications and consequences of the underlying disease, resulting in side effects drugs, or accidentally combined manifestation of disease. Etiology and pathogenesis of these symptoms and their relationship with IBD often are not clear. Knowledge of extraintestinal manifestations is of paramount practical importance for the early diagnosis of IBD when other symptoms, including intestinal and may either be absent or subclinical, extraintestinal manifestations and complications come to the fore in clinical picture, leading to inappropriate treatment and, therefore, determines a poor prognosis.